This easy Instant Pot Mississippi Pot Roast Recipe is a dump-and-go dinner, packed with flavor, and perfect for busy weeknights. It’s a classic pot roast recipe made with chuck roast, ranch seasoning, au jus gravy, pepperoncini peppers, and butter that's pressure-cooked until tender and juicy in about an hour.
Season the roast with salt and pepper on all sides and trim excess fat.
Set the Instant Pot to 'Sauté' mode and add olive oil. Once hot, sear the roast chunks on all sides until browned, about 3-4 minutes per side. Remove and set aside.
Add the beef broth to the Instant Pot, scraping the bottom to release any browned bits.
Place the roast back into the Instant Pot. Add the pepperoncini peppers, their juice, au jus mix, ranch seasoning, and the stick of butter on top of the roast.
Close the lid and set the Instant Pot to 'Pressure Cook' (Manual) on high for 60-80 minutes (or 20 minutes per pound of meat). Allow a natural release for 15 minutes, then quick release any remaining pressure.
Carefully remove the roast from the Instant Pot, shred with two forks, and mix with the juices before serving.
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Notes
Storage Store any leftover Mississippi Pot Roast with gravy in an airtight container in the refrigerator for up to 3 days.Freeze Place the cooked and cooled pot roast in an airtight container or freezer bag for up to 3 months, then reheat gently when ready to serve.Reheat To reheat, warm it gently in a skillet over low heat until just heated through.Substitutions
Beef Chuck Roast: Can be substituted with brisket or pork shoulder for a different flavor.
Pepperoncini Peppers: Use banana peppers for a milder taste.
Ranch Seasoning Mix: Replace with Italian seasoning.
Adjustments Cooking time may need to be adjusted based on the geography of the area (high vs. low elevation), cookware (stoneware vs traditional bakeware), and outdoor temperature if grilling.Nutrition information is only an estimate