If you're looking for a flavorful, easy pot roast recipe that’s perfect for weeknight meals, this Easy Instant Pot Mississippi Pot Roast Recipe is your answer. Combining the convenience of a pressure cooker with the incredible flavor of slow-cooked beef, this dish is sure to become a family favorite.
Need a pairing idea? Serve this over our Jasmine Rice Instant Pot Recipe with a side of Old Fashioned Cucumbers and Onions in Vinegar or some Skillet Cornbread.

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Mississippi Pot Roast originated from a home cook in Mississippi. Traditionally made with beef chuck roast, pepperoncini peppers, ranch seasoning mix, au jus gravy mix, and butter, it’s the ultimate comfort food.
If you like this recipe, you may also love our Slow Cooker Chuck Roast with Tender Vegetables and Gravy, Authentic Cuban Ropa Vieja Recipe in the Slow Cooker or this Easy Instant Pot Mojo Pork.
Why We Love This Recipe
- Quick and Easy: Ready in just over an hour thanks to the Instant Pot.
- Flavorful and Tender: The combination of pepperoncini peppers and ranch seasoning mix creates a unique and delicious taste.
- Family-Friendly: Loved by kids and adults alike, making it a perfect family dinner.
- Versatile: Great for weeknight meals, entertaining, or as a leftover for the next day.
Instant Pot Mississippi Pot Roast Ingredients
- Beef Chuck Roast: A well-marbled cut that becomes tender and flavorful when cooked.
- Unsalted Butter: Adds richness without making the dish too salty.
- Pepperoncini Peppers: Adds a tangy and mildly spicy flavor to the roast. Have leftover peppers? We love adding these to our family favorite Pepperoni Rolls!
- Ranch Seasoning Mix: Provides a creamy, herby taste that complements the beef.
- Au Jus Gravy Mix: Adds to the savory flavor of the beef and creates a delicious gravy.
- Beef Broth: Keeps the roast moist and adds depth to the sauce.
- Olive Oil: Used for searing the roast to lock in flavor.
- Salt and Pepper: Basic seasonings to enhance the overall taste.
A full ingredient list with exact measurements can be found in the recipe card below.
Substitutions & Variations
- Beef Chuck Roast: Can be substituted with brisket or pork shoulder for a different flavor.
- Pepperoncini Peppers: Use banana peppers for a milder taste.
- Ranch Seasoning Mix: Replace with Italian seasoning.
- Diet-Friendly: Use low-sodium beef broth and unsalted butter to reduce sodium content.
How to Make Instant Pot Mississippi Pot Roast
STEP ONE: Prepare the Roast
Season the beef chuck roast with salt and pepper. Set your Instant Pot to 'Sauté' mode and add olive oil. Once hot, sear the roast on all sides until browned, about 4-5 minutes per side. Remove and set aside
STEP TWO: Deglaze the Pot
Pour the beef broth into the Instant Pot, scraping the bottom to release any browned bits. This step adds extra flavor to your pot roast.
STEP THREE: Add Ingredients
Place the roast back into the Instant Pot. Add the pepperoncini peppers, their juice, au jus mix, ranch seasoning, and the stick of butter on top of the roast.
STEP FOUR: Pressure Cook
Close the lid and set the Instant Pot to 'Pressure Cook' (Manual) on high for 60-80 minutes (20 minutes per pound). Allow a natural release for 15 minutes, then quick release any remaining pressure.
Carefully remove the roast, shred it with two forks, and mix it back into the juices before serving.
Expert Tips for Success
👩🍳Jami's Pro Tips: Want to take this recipe to the next level? Check out my expert tips below for the best flavor, texture, and meal prep hacks!
✔️ DO Sear the roast before pressure cooking to add flavor.
✔️ DO Do release pressure naturally for 15 minutes to help keep the meat tender.
Storage
Store any leftover Mississippi Pot Roast in an airtight container in the refrigerator for up to 3 days. To freeze, store the cooked and cooled pot roast in an airtight container or freezer bag for up to 3 months, then reheat gently when ready to serve.
Recipe FAQs
Yes, you can make Mississippi pot roast in a slow cooker by cooking on low for 8 hours.
To reduce the saltiness, use low-sodium beef broth and unsalted butter. You can also rinse the pepperoncini peppers before adding them to the pot roast.
If you don't have au jus gravy mix, you can use a packet of brown gravy mix or make a simple beef broth gravy by combining beef broth with a bit of cornstarch or flour for thickening.
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📖 Recipe
Easy Instant Pot Mississippi Pot Roast Recipe with Pepperoncini
Equipment
- Instant Pot or Pressure Cooker
- Tongs
- Measuring cups and spoons
- Cutting board
- Chef’s Knife
Ingredients
- 3-4 lb roast mock tender or chuck
- 1 stick unsalted butter
- 8-10 pepperoncini peppers with ¼ cup of the juice
- ½ packet of au jus mix
- ½ packet of ranch seasoning
- ½ cup beef broth
- 2-3 tablespoons olive oil
- salt and pepper to taste
Instructions
- Season the roast with salt and pepper on all sides.
- Set the Instant Pot to 'Sauté' mode and add olive oil. Once hot, sear the roast on all sides until browned, about 4-5 minutes per side. Remove and set aside.
- Add the beef broth to the Instant Pot, scraping the bottom to release any browned bits.
- Place the roast back into the Instant Pot. Add the pepperoncini peppers, their juice, au jus mix, ranch seasoning, and the stick of butter on top of the roast.
- Close the lid and set the Instant Pot to 'Pressure Cook' (Manual) on high for 60-80 minutes (or 20 minutes per pound of meat). Allow a natural release for 15 minutes, then quick release any remaining pressure.
- Carefully remove the roast from the Instant Pot, shred with two forks, and mix with the juices before serving.
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Notes
- Beef Chuck Roast: Can be substituted with brisket or pork shoulder for a different flavor.
- Pepperoncini Peppers: Use banana peppers for a milder taste.
- Ranch Seasoning Mix: Replace with Italian seasoning.
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